Mass Spectrometry in the news!

by Brian | 13th July 2009

Funny the properties of coincidence: you only notice them when they are happening. (Corollary: you don’t notice the near infinite things which are not coincidence which are continually happening.) My mind has been filled with refining the MSMSFit alogirthm and along comes this Wired article talking about the mass spectrometry analysis of a T. Rex bone. It references trypsin digestion, peak lists and “labyrinthine mathematical algorithms”.

A funny parallel to the article is that when I was testing out MSMSFit I wanted to run a test case which would produce all wong results so I used it to try to locate a human protein in E. Coli. What was kind of interesting was that there were too fairly promising “hits” at about the same location in the genome. These were not strong hits, but I thought that perhaps this is protein could be a very distant cousin of one in E. Coli.

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